What Can fMRI Tell Us About Mental Illness?

A remarkable and troubling new paper: Addressing reverse inference in psychiatric neuroimaging: Meta-analyses of task-related brain activation in common mental disorders

Icahn School of Medicine researchers Emma Sprooten and colleagues carried out an ambitious task: to pull together the results of every fMRI study which has compared task-related brain activation in people with a mental illness and healthy controls.

Sprooten et al.’s analysis included 537 studies with a total of 21,427

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