Back in 2013, a Nature Reviews Neuroscience paper appeared called Power failure: why small sample size undermines the reliability of neuroscience. This paper got a lot of attention at the time and has since been cited a dizzying 1760 times according to Google.
‘Power Failure’ made waves for its stark message that most neuroscience studies are too small, leaving neuroscience lacking statistical power, the chance of detecting signal in the noise. As the authors Kate Button et al. wrote